Immunohaematology studies the reactions that take place between antigens present on blood cells and antibodies present in plasma. Patients undergoing transfusion therapy are tested for their ABO and RhD blood groups and the presence of any antibodies that may cause a reaction between their plasma and donor red cells. A range of tests are available to use to detect and identify antibodies in the patient's plasma from simple tube and gel tests to more complex absorption and elution techniques as well as advanced molecular techniques. These same tests will also identify if the antigen is present on the patient's red cells. For patients with haematological conditions such as auto immune haemolytic anaemia, a wide range of immune-haematological techniques are used to identify and resolve the diagnostic problems in these patients. Molecular techniques are increasingly used in immunohaematology to determine the antigen profile of patients, resolve complex problems and large scale red cell typing.
We bring together ISBT members working in the field of immunohaematology and focus on practical subjects common to Immunohaematology practice. We discuss educational activities, website communications, exchanges of information and rare samples, recommendations for best practice, supporting developing countries in an advisory capacity. We also promote best practice and facilitate improvements in Immunohaematology through education, communication, exchange of ideas/resources and support in the areas of red cell serology, molecular testing, antigen/allele matching and transfusion recommendations.
Our Chairperson is Thierry Peyrard.
We meet at the ISBT congresses and focus on additional education venues such as website communications, immunohaematology forum, list of references specific to immunohaematology topics and recommendations for minimal testing.
Any ISBT member can join if they have a career focus on immunohaematology. Over-representation of countries or organizations will be monitored by the Executive Committee of the WP and may be limited. Industry representatives can only attend our meetings as guests.
Interested in joining the Immunohaematology WP? Please email our Chairperson.
Some of the content is only accessible for ISBT-members. To join us, click here.
Follow this link to visit the ISBT Academy ePortal and watch the webcast of Nicole Thornton. The talk was recorded at the 33rd International Congress of the ISBT in Seoul.
- Bleeding or no bleeding? Anti‐endothelial alphaVbeta3 antibodies as a major cause of intracranial haemorrhage in fetal–neonatal alloimmune thrombocytopenia ISBT Science Series 2017 Dec; 13, 59–69, doi.org/10.1111/voxs.12401
- Update on the nomenclature of human neutrophil antigens and alleles Transfusion. 2016 Jun;56(6):1477-9.
- External quality assessment of human neutrophil antigen (HNA)-specific antibody detection and HNA genotyping from 2000 to 2012 Vox Sang. 2013 Oct;105(3):259-69.
The workshop on the clinical significance of red cell alloantibodies was organised by the Executive Committee of the ISBT Working Party on Immunohaematology (WPIH) and took place in Dubai on 9th September for one whole day in conjunction with the 34th International Congress of the ISBT.
One of the focal points of the Working Party on Immunohematology is to provide information and educational opportunities through the ISBT Working Party Website. The Immunohematology Case Studies are popular formats for small and large group meetings; they give the opportunity to study cases that the participants may not see often but should be able to identify and to learn new practical approaches that may be used in their institution.
Twelve members of the Working Party on Immunohematology will share 1 case study each. These cases will hopefully be valuable as learning tools for all levels of those interested in immunohematology. Your comments and feedback are most welcomed.
The first five chapter of the Immunohematology Case studies are freely accessible.