Live Journal Club
On March 0, 2023, the TER coordinators Allison Mo, Susan Brunskill and Catherin Kimber held a Live Journal Club where they invited the reviewers to discuss selected papers from the Round-Up.
Welcome to the quarterly Transfusion Evidence Round-Up. This is a collaboration between the International Society of Blood Transfusion (ISBT) and the Transfusion Evidence Library (TEL). We aim to highlight high quality evidence randomised controlled trials and systematic reviews about an internationally relevant subject in the field of Transfusion Medicine. All references are drawn from the Transfusion Evidence Library and, where relevant, Stem Cell Evidence.
The Transfusion Evidence Round-Up is traditionally sent to ISBT members and TEL subscribers. Given our upcoming open-access Live Journal Club for World Haemophilia Day, we are sending this edition to a wider audience. We hope to see you at the event. In the meantime enjoy this selection of articles. If you are not an ISBT member yet but would like to become one to continue receiving these emails you can sign-up here.
The Transfusion Evidence Library is produced by the Systematic Review Initiative (SRI) and funded by the four UK blood services. It is available free at the point of access providing a comprehensive and up-to-date database of high-quality evidence in Transfusion Medicine.
The International Society of Blood Transfusion (ISBT) is a scientific society creating a community of transfusion medicine professionals from around the globe. ISBT works towards its vision of "a world of safe and sufficient blood" by undertaking advocacy for patient and donor safety, sharing knowledge to enhance transfusion practice and providing opportunities for education.
Top 10 articles
Ten articles are highlighted to bring attention to Bleeding Disorders: World Haemophilia Day 2023.
These articles have been identified from the Transfusion Evidence Library and selected by ISBT members: Dr Lyuben Georgiev, Dr Jessica Guglielmino, and Professor Gesine Weckmann.
Platelet-to-red blood cell ratio and mortality in bleeding trauma patients: A systematic review and meta-analysis Kleinveld DJB ; van Amstel RBE ; Wirtz MR ; Geeraedts LMG ; Goslings JC ; Hollmann MW ; Juffermans NP Transfusion. 2021
These articles were discussed during the Live Journal Club.
Platelet-to-red blood cell ratio and mortality in bleeding trauma patients: A systematic review and meta-analysis.
Kleinveld, D.J.B., et al. (2021). Transfusion.
IVMP+IVIG raises platelet counts faster than IVIG alone: results of a randomized, blinded trial in childhood ITP.
Carcao, M., et al. (2020). Blood Advances.
Effects of replacement therapies with clotting factors in patients with hemophilia: A systematic review and meta-analysis.
Delgado-Flores, C.J., et al. (2022). PlosOne.
Comparative efficacy and safety of thrombopoietin receptor agonists in adults with thrombocytopenia: A systematic review and network meta-analysis of randomized controlled trial.
Deng, J., et al. (2021). Frontiers in Pharmacology.
Risk factors for bleeding in people living with Hemophilia A and B treated with regular prophylaxis: a systematic review of the literature.
Germini, F., et al. (2022). Journal of Thrombosis and Haemostasis.
The impact of recombinant versus plasma-derived factor VIII concentrates on inhibitor development in previously untreated patients with hemophilia A: A 2021 update of a systematic review and meta-analysis.
Kohar, K., Prayogo, S.A., and Wiyono, L., (2022). Cureus.
Pre-procedural use of thrombopoietin-receptor agonists in cirrhosis and severe thrombocytopenia: A systematic review and meta-analysis.
Rose, P.D., et al. (2021). Digestive and Liver Disease.
Risk of thrombosis with thrombopoietin receptor agonists for ITP patients: a systematic review and meta-analysis.
Tjepkema, M., Amini, S., and Schipperus, M., (2022). Critical Reviews in Oncology/Hematology.
Comparative efficacy of 19 drug therapies for patients with idiopathic thrombocytopenic purpura: a multiple-treatments network meta-analysis.
Zhou, H., et al. (2022). Annals of Hematology.
Incidence and mortality rates of intracranial hemorrhage in hemophilia: a systematic review and meta-analysis.
Zwagemaker, A.F., et al. (2021). Blood.
Systematic Research Initiative
The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion
Transfusion Evidence Library
The Transfusion Evidence Library is a database of systematic reviews and randomised controlled trials relevant to transfusion medicine. It is fully searchable, updated monthly and aims to be a key resource for medical practitioners, policy makers and researchers both in the UK and around the world. A monthly email: The Transfusion Evidence Alert with the latest top 10 records is sent to subscribers. The library is produced by the Systematic Review Initiative and funded by the UK Blood Services.
Stem Cell Evidence
Stem Cell Evidence is a comprehensive collection of high quality research relevant to haematopoietic stem cell transplantation, updated monthly. The most important articles in the field are highlighted in the Stem Cell Evidence Alert which is a newsletter emailed to subscribers. Stem Cell Evidence aims to be a key resource worldwide for medical practitioners, clinical researchers and policy makers. It is also intended to be of value to those planning new clinical trials in the field. It is produced by the Systematic Review Initiative and funded by the UK Blood Services and Oxford Biomedical Research Centre.