This webinar will provide an evidence-based overview of exchange transfusion in sickle cell disease, focusing on current guidelines, clinical outcomes, and best practices. It aims to bridge research findings with practical applications in transfusion medicine and therapeutic apheresis.
Level of education required:
Intermediate (Practical application)
What knowledge is required?
It is good to have basic knowledge on ABO incompatible hematopoietic stem cell transplantation ad blood groups change after HSCT.
Attendees are encouraged to read the following articles:
- Adkins BD, Jacobs JW, Booth GS, Savani BN, Stephens LD. Transfusion Support in Hematopoietic Stem Cell Transplantation: A Contemporary Narrative Review. Clin Hematol Int. 2024 Mar 25;6(1):128-140. doi: 10.46989/001c.94135. PMID: 38817704; PMCID: PMC11086996.
- Matteocci A, Pierelli L. Immuno-Hematologic Complexity of ABO-Incompatible Allogeneic HSC Transplantation. Cells. 2024 May 10;13(10):814. doi: 10.3390/cells13100814. PMID: 38786038; PMCID: PMC11119197.
- Jekarl DW, Kim JK, Han JH, Lee H, Yoo J, Lim J, Kim Y. Transfusion support in hematopoietic stem cell transplantation. Blood Res. 2023 Apr 30;58(S1):S1-S7. doi: 10.5045/br.2023.2023004. Epub 2023 Feb 27. PMID: 36843378; PMCID: PMC10133853.
- Migdady Y, Pang Y, Kalsi SS, Childs R, Arai S. Post-hematopoietic stem cell transplantation immune-mediated anemia: a literature review and novel therapeutics. Blood Adv. 2022 Apr 26;6(8):2707-2721. doi: 10.1182/bloodadvances.2021006279. PMID: 34972204; PMCID: PMC9043947.
- Shokrgozar N, Tamaddon G. ABO Blood Grouping Mismatch in Hematopoietic Stem Cell Transplantation and Clinical Guides. Int J Hematol Oncol Stem Cell Res. 2018 Oct 1;12(4):322-328. PMID: 30774834; PMCID: PMC6375375.
- Schrezenmeier H, Körper S, Höchsmann B, et al. Transfusion Support. 2024 Apr 11. In: Sureda A, Corbacioglu S, Greco R, et al., editors. The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies [Internet]. 8th edition. Cham (CH): Springer; 2024. Chapter 24. Available from: https://www.ncbi.nlm.nih.gov/books/NBK608283/ doi: 10.1007/978-3-031-44080-9_24
Target audience
- Transfusion practitioners and blood bankers
- Hematopoietic stem cell transplantation physicians
- Clinical practitioners
- Scientists, technicians and medical students.
The Speaker
Fatma Burcu Belen Apak
Richard R. Gammon will be the moderator at this webinar.
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